BDBM50616425 CHEMBL5398837

SMILES COc1ccc2c(c1)sc3n2cnn3

InChI Key InChIKey=VBZWNZIFSFRMTM-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50616425   

TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616425(CHEMBL5398837)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP15 (unknown origin) expressed in Escherichia coli in presence of NAD+More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616425(CHEMBL5398837)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal TNKS2 (unknown origin) expressed in Escherichia coli in presence of NAD+More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616425(CHEMBL5398837)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP10 (unknown origin) expressed in Escherichia coli in presence of NAD+More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50616425(CHEMBL5398837)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of N-terminal MBP tagged/C-terminal PARP2 (unknown origin) expressed in Escherichia coli in presence of NAD+More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details Article
PubMed