BDBM50641145 CHEMBL5566862

SMILES CNc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)n(CCCCCO)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50641145   

TargetSerine/threonine-protein kinase SIK2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641145(CHEMBL5566862)
Affinity DataEC50:  266nMAssay Description:Inhibition of SIK2 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641145(CHEMBL5566862)
Affinity DataEC50:  316nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641145(CHEMBL5566862)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of MST4 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641145(CHEMBL5566862)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of MST2 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50641145(CHEMBL5566862)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of MST1 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed