BDBM50644790 CHEMBL5575056

SMILES CC[C@H](CO)Nc1nc(c2c(n1)n(cn2)C(C)C)NCC3=CC=C(C(=O)N3)c4ccccn4

InChI Key InChIKey=ZZMGLCCXIBNSGN-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50644790   

TargetCyclin-dependent kinase 12(Human)
UCB

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50644790BDBM50644790(CHEMBL5575056)
Affinity DataEC50:  21nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)