BDBM50657690 CHEMBL6160170

SMILES Cc1cn(C)nc1Nc1cc2cc(C3CCc4nccn43)nc(N)c2cn1

InChI Key InChIKey=PGCMMHIBMGQQPC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50657690   

LigandChemical structure of BindingDB Monomer ID 50657690BDBM50657690(CHEMBL6160170)
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human MASTL (1 to 879 residues) expressed in baculovirus infected Sf21 cells using AQT0693 as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50657690BDBM50657690(CHEMBL6160170)
Affinity DataIC50: 163nMAssay Description:Inhibition of MASTL in human MDA-MB-231 cells assessed as reduction in ENSA phosphorylation incubated for 1 hr by sandwich ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed