BDBM506646 US12534452, Example 230

SMILES CN1CCN(C(=O)CCCc2cn(-c3ccccc3)c(NC(=O)c3cccc(-c4cn[nH]c4F)c3)n2)CC1

InChI Key InChIKey=FWSIEEFERGMLJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506646   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kainos Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 506646BDBM506646(US12534452, Example 230)
Affinity DataIC50: 50nMAssay Description:The mGluR5 activity was determined using the metabotropic glutamate receptor activity assays in human embryonic kidney cell.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent