BDBM50667075 CHEMBL6165710

SMILES CC(C)c1cc(C(=O)N2C[C@@H](c3ccccc3)C[C@@H]2C(=O)NCCCN2CCOCC2)c(O)cc1O

InChI Key InChIKey=HWJIITQBZMFBTJ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50667075   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667075BDBM50667075(CHEMBL6165710)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Hsp90 (unknown origin) ATPase activity assessed as decrease in absorbance using PEP as substrate in presence of ATP and NADH by absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667075BDBM50667075(CHEMBL6165710)
Affinity DataKd:  87nMAssay Description:Binding affinity to Hsp90 (unknown origin) assessed as dissociation constant incubated for 30 mins by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667075BDBM50667075(CHEMBL6165710)
Affinity DataIC50: 154nMAssay Description:Inhibition of HSP90alpha (unknown origin) incubated for 12 to 16 hrs by FP competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEndoplasmin(Human)
Dezhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667075BDBM50667075(CHEMBL6165710)
Affinity DataIC50: 773nMAssay Description:Inhibition of GRP94 (unknown origin) incubated for 12 to 16 hrs by FP competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed