BDBM506727 US12534458, Example 6

SMILES Cc1ccccc1-c1cccc([C@@H]2C(F)(F)C23CCN(S(N)(=O)=O)CC3)n1

InChI Key InChIKey=OZNZEVSZLQWQLB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506727   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 506727BDBM506727(US12534458, Example 6)
Affinity DataEC50:  2.20E+3nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent