BDBM531713 3-(5-(2-(4-((4'-chloro-[1,1'-biphenyl]-2- yl)methyl)piperazin-1-yl)ethyl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-05876

SMILES O=C1CCC(N2Cc3c(CN4CCN(Cc5ccccc5-c5ccc(Cl)cc5)CC4)cccc3C2=O)C(=O)N1

InChI Key InChIKey=TUAWVMVWEVAELN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531713   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531713BDBM531713(3-(5-(2-(4-((4'-chloro-[1,1'-biphenyl]-2- yl)methy...)
Affinity DataIC50: 120nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent