BDBM531717 3-(5-(((1R,4R)-5-((4'-chloro-5,5-dimethyl- 3,4,5,6-tetrahydro-[1,1'-biphenyl]-2- yl)methyl)-2,5-diazabicyclo[2.2.1]heptan- 2-yl)methyl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20260028326, Compound GT-03887

SMILES CC1(C)CCC(CN2C[C@H]3C[C@@H]2CN3Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=GKUJYDYWOSWJHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531717   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531717BDBM531717(3-(5-(((1R,4R)-5-((4'-chloro-5,5-dimethyl- 3,4,5,6...)
Affinity DataIC50: 190nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent