BDBM531822 3-(5-(2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-[1,1'-biphenyl]-2- yl)methyl)piperazin-1-yl)ethyl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-05361

SMILES CC1(C)CCC(CN2CCN(CCc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=GNKBJUAWLGNEQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531822   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531822BDBM531822(3-(5-(2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6- tetra...)
Affinity DataIC50: 370nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent