BDBM531847 5-(5-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-[1,1'-biphenyl]-2-yl)methyl)- 2,5-diazabicyclo[2.2.2]octan-2-yl)-2-(2,6- dioxopiperidin-3-yl)isoindoline-1,3-dione::US20260028326, Compound GT-05379

SMILES CC1(C)CCC(CN2CC3CCC2CN3c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=VRMNRXJDVFVMTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531847   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531847BDBM531847(5-(5-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-...)
Affinity DataIC50: 110nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent