BDBM531852 3-(5-((4-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-[1,1'-biphenyl]-2-yl)methyl)-2- (trifluoromethyl)piperazin-1-yl)methyl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-05796

SMILES CC6(C)CCC(CN4CCN(Cc3ccc2C(=O)N(C1CCC(=O)NC1=O)Cc2c3)C(C(F)(F)F)C4)=C(c5ccc(Cl)cc5)C6

InChI Key InChIKey=UKXPXVOPSCPXOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 531852   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 531852BDBM531852(3-(5-((4-((4'-chloro-5,5-dimethyl-3,4,5,6- tetrahy...)
Affinity DataIC50: 200nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent