BDBM533798 US11225469, Compound 46

SMILES Cc1ccnc(c1)NC(=S)Nc2cccc(c2)C(F)(F)F

InChI Key InChIKey=FSUJUFLZGYFLEM-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 533798   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Whitehead Institute For Biomedical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 533798BDBM533798(US11225469, Compound 46)
Affinity DataIC50: 1.50E+4nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent