BDBM535900 3-(5-((6-(4'-chloro-5,5-dimethyl-3,4,5,6- tetrahydro-[1,1'-biphenyl]-2-carbonyl)-2,6- diazaspiro[3.3]heptan-2-yl)methyl)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-05681

SMILES CC1(C)CCC(C(=O)N2CC3(CN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)C2)=C(c2ccc(Cl)cc2)C1

InChI Key InChIKey=BQFHUFOCRICLHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535900   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 535900BDBM535900(3-(5-((6-(4'-chloro-5,5-dimethyl-3,4,5,6- tetrahyd...)
Affinity DataIC50: 460nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent