BDBM535959 3-(5-((1-(4'-chloro-[1,1'-biphenyl]-2- carbonyl)azetidin-3-yl)amino)-1- oxoisoindolin-2-yl)piperidine-2,6-dione::US20260028326, Compound GT-04397

SMILES O=C1CCC(N2Cc3cc(NC4CN(C(=O)c5ccccc5-c5ccc(Cl)cc5)C4)ccc3C2=O)C(=O)N1

InChI Key InChIKey=PGUGBVPIPNATNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535959   

TargetProtein cereblon(Human)
Gluetacs Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 535959BDBM535959(3-(5-((1-(4'-chloro-[1,1'-biphenyl]-2- carbonyl)az...)
Affinity DataIC50: 200nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent