BDBM540222 (R)-4-(3-(1-(3-(difluoromethyl)-1-(2,2-dimethylpiperidin-4-yl)-1H-pyrazol-4-yl)-1,2,3-triazol-4-yl]pyrazolo[1,5-a]pyrimidin-5-yl)morpholine::US20260028337, Compound 86A

SMILES CC1(C)C[C@H](n2cc(-n3cc(-c4cnn5ccc(N6CCOCC6)nc45)nn3)c(C(F)F)n2)CCN1

InChI Key InChIKey=OSNNSJUZOGNTCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540222   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540222BDBM540222((R)-4-(3-(1-(3-(difluoromethyl)-1-(2,2-dimethylpip...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent