BDBM540231 4-(3-(difluoromethyl)-4-(4-(5-(4-methylpiperazin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1H-1,2,3-triazol-1-yl)-1H-pyrazol-1-yl)cyclohexylmethanol::US20260028337, Compound 95A

SMILES CN1CCN(c2ccn3ncc(-c4cn(-c5cn(C6CCC(CO)CC6)nc5C(F)F)nn4)c3n2)CC1

InChI Key InChIKey=RUXKADRNQJDXEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540231   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540231BDBM540231(4-(3-(difluoromethyl)-4-(4-(5-(4-methylpiperazin-1...)
Affinity DataIC50: 550nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent