BDBM540239 (4-(4-(4-(5-((S)-3-aminopiperidin-1-yl) pyrazolo[1,5-a]pyrimidin-3-yl)-1H-1,2,3-triazol-1-yl)-3-(difluoromethyl)-1H-pyrazol-1-yl)cyclohexyl)methanol::US20260028337, Compound 103A

SMILES N[C@H]1CCCN(c2ccn3ncc(-c4cn(-c5cn(C6CCC(CO)CC6)nc5C(F)F)nn4)c3n2)C1

InChI Key InChIKey=GWUGWFJRPBAKNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540239   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540239BDBM540239((4-(4-(4-(5-((S)-3-aminopiperidin-1-yl) pyrazolo[1...)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent