BDBM540246 2-((3-(1-(3-(difluoromethyl)-1-(4-(methylol)cyclohexyl)-1H-pyrazol-4-yl)-1H-1,2,3-triazol-4-yl]pyrazolo[1,5-a]pyrimidin-5-yl)amino)cyclohexan-1-ol::US20260028337, Compound 111A

SMILES OCC1CCC(n2cc(-n3cc(-c4cnn5ccc(NC6CCCCC6O)nc45)nn3)c(C(F)F)n2)CC1

InChI Key InChIKey=HNVODEXQTBBMDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540246   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shenzhen Zhongge Biological Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 540246BDBM540246(2-((3-(1-(3-(difluoromethyl)-1-(4-(methylol)cycloh...)
Affinity DataIC50: 100nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent