BDBM563823 Roche-Dataset for PDE10A, Compound 137

SMILES Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1cn(cn1)-c1ccc2ccccc2n1

InChI Key InChIKey=HLOIHBUUYVDORH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563823   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
F. Hoffmann-La Roche

LigandBDBM563823(Roche-Dataset for PDE10A, Compound 137)Copy SMILESCopy InChI

Affinity DataIC50: 0.700nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL