BDBM563996 Roche-Dataset for PDE10A, Compound 310

SMILES Clc1cc(NC(=O)c2ccc3cc(nn3c2)-c2ccccc2)ccn1

InChI Key InChIKey=DPLIZFKHTDLAGO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563996   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
F. Hoffmann-La Roche

LigandBDBM563996(Roche-Dataset for PDE10A, Compound 310)Copy SMILESCopy InChI

Affinity DataIC50: 37nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL