BDBM564083 Roche-Dataset for PDE10A, Compound 397

SMILES Cn1c(c(cn1)C(=O)N2CCC2)C(=O)Nc3ccc4c(c3)nc(s4)N5CCOCC5

InChI Key InChIKey=KINFQXODKGZLHD-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564083   

LigandChemical structure of BindingDB Monomer ID 564083BDBM564083(Roche-Dataset for PDE10A, Compound 397)
Affinity DataIC50: 1.86nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed