BDBM564181 Roche-Dataset for PDE10A, Compound 495

SMILES Cc1ccccc1-c1cn2CC[C@H](Cc2n1)NC(=O)c1c(cnn1C)C(=O)N1CCC1

InChI Key InChIKey=UGNUIDFPGQXYSB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564181   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
F. Hoffmann-La Roche

LigandBDBM564181(Roche-Dataset for PDE10A, Compound 495)Copy SMILESCopy InChI

Affinity DataIC50: 7.85nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details Article
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