BDBM578522 3-methoxy-5,5- dimethyl-6-oxo- 3-(3- (trifluoromethoxy)py- ridin-2- yl)cyclohex-1- enecarbonitrile (Enantiomer A)::US11479539, Compound 147::US11479539, Compound 41

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncccc1OC(F)(F)F

InChI Key InChIKey=XZXFTEAYUOLRJW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578522   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578522(3-methoxy-5,5- dimethyl-6-oxo- 3-(3- (trifluoromet...)
Affinity DataEC50:  11nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578522(3-methoxy-5,5- dimethyl-6-oxo- 3-(3- (trifluoromet...)
Affinity DataEC50:  22nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent