BDBM578551 3-[3-(1,5- dimethyl-1H- pyrazol-4-yl)-5- fluoropyridin-2- yl]-3-methoxy- 5,5-dimethyl-6- oxocyclohex-1- ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 164::US11479539, Compound 71
SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1cnn(C)c1C
InChI Key InChIKey=XCLXMEDPMVEGKV-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 578551
Affinity DataEC50: 9nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair