BDBM578561 3-[5-fluoro-3-(1- phenylpyrazol-4- yl)-2-pyridyl]-3- methoxy-5,5- dimethyl-6-oxo- cyclohexene-1- carbonitrile (Enantiomer A)::US11479539, Compound 179::US11479539, Compound 81

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1cnn(c1)-c1ccccc1

InChI Key InChIKey=ASJDEQQOORAVDF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578561   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578561(3-[5-fluoro-3-(1- phenylpyrazol-4- yl)-2-pyridyl]-...)
Affinity DataEC50:  2nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578561(3-[5-fluoro-3-(1- phenylpyrazol-4- yl)-2-pyridyl]-...)
Affinity DataEC50:  7nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent