BDBM578570 3-[5-fluoro-3-[6- (trifluoromethyl)- 3-pyridyl]-2- pyridyl]-3- methoxy-5,5- dimethyl-6-oxo- cyclohexene-1- carbonitrile (Enantiomer A)::US11479539, Compound 90

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=ISMCZYHZJXDDSR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578570   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578570(3-[5-fluoro-3-[6- (trifluoromethyl)- 3-pyridyl]-2-...)
Affinity DataEC50:  11nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent