BDBM578574 3-(5-fluoro-5'- (methylsulfonyl)- [3,3'-bipyridin]- 2-yl)-3-methoxy- 5,5-dimethyl-6- oxocyclohex-1- ene-1- carbonitrile::US11479539, Compound 235::US11479539, Compound 96

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1cncc(c1)S(C)(=O)=O

InChI Key InChIKey=UKSQFPLHWJYMNO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578574   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578574(3-(5-fluoro-5'- (methylsulfonyl)- [3,3'-bipyridin]...)
Affinity DataEC50:  7nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578574(3-(5-fluoro-5'- (methylsulfonyl)- [3,3'-bipyridin]...)
Affinity DataEC50:  79nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent