BDBM578686 3-[5'-(2-cyanopropan-2- yl)-5-fluoro[3,3'- bipyridin]-2-yl]-3- methoxy-5,5-dimethyl- 6-oxocyclohex-1-ene-1- carbonitrile (Enantiomer A)::US11479539, Compound 222

SMILES COC1(CC(C)(C)C(=O)C(=C1)C#N)c1ncc(F)cc1-c1cncc(c1)C(C)(C)C#N

InChI Key InChIKey=GKAUXWBQWHCYAU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578686   

Targethek293 luciferase(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune

US Patent
LigandPNGBDBM578686(3-[5'-(2-cyanopropan-2- yl)-5-fluoro[3,3'- bipyrid...)
Affinity DataEC50:  6nMAssay Description:Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent