BDBM629381 US20230339981, Example 68

SMILES C[C@]12CC[C@H](N1)[C@H]1CCc3nc(c(F)c4nc(OCC5(CN6CCC(F)CC6)CC5)nc(N1C2)c34)-c1cc(O)cc2ccc(F)c(C#C)c12

InChI Key InChIKey=UDTBHYBNCBZVHC-ZRPFIRPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 629381   

TargetGTPase KRas [G12D](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM629381(US20230339981, Example 68)
Affinity DataIC50:  0.0500nMAssay Description:Compounds were tested for binding to GDP-loaded KRAS G12D in a 384-well assay format using a TR-FRET probe displacement assay in buffer consisting of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent