BDBM657138 US11926614, Example 135

SMILES CCOc1ccc(-c2nnc([C@H]3C[C@H](NC(=O)c4ccnc5cccnc45)C3)n2-c2ccccc2Cl)nc1

InChI Key InChIKey=YGQJTDMFOBJBPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657138   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandChemical structure of BindingDB Monomer ID 657138BDBM657138(US11926614, Example 135)
Affinity DataIC50: 1.90nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent