BDBM67081 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoic acid [2-(3,4-dimethylanilino)-2-oxoethyl] ester::3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propionic acid [2-(3,4-dimethylanilino)-2-keto-ethyl] ester::MLS002157858::SMR001240340::[2-(3,4-dimethylanilino)-2-oxoethyl] 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate::[2-[(3,4-dimethylphenyl)amino]-2-oxidanylidene-ethyl] 3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)propanoate::cid_4782538

SMILES COc1cc(F)c(-c2ccc(N3CCC[C@](N)([C@H](O)C(F)F)C3)c(Cn3cnc4c(N)ncnc43)c2)cc1F

InChI Key InChIKey=KTVJZZDBABXCNG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67081   

TargetHistone-lysine N-methyltransferase NSD2(Human)
K36 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 67081BDBM67081(US20250361235, Compound I-1)
Affinity DataIC50: 5.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent