BDBM67498 US20250361241, Compound 145

SMILES CC(=O)N1Cc2nc(Nc3ccc(-c4cnc5cc(F)ccn45)c4c3C(=O)NC4)ccc2C2(CCCCC2)C1

InChI Key InChIKey=ITVOIJZUSZICMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67498   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67498BDBM67498(US20250361241, Compound 145)
Affinity DataIC50: 38.1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent