BDBM679667 US20240182487, Compound 66

SMILES CCc1c2\C=C\c3n[nH]c4cnc(cc34)-c3cc(OC)ncc3OCCN(C)C(=O)c2nn1C

InChI Key InChIKey=YPPCWFIHKRMIEV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679667   

TargetEpidermal growth factor receptor [L858R](Human)
Blossomhill Therapeutics

US Patent
LigandPNGBDBM679667(US20240182487, Compound 66)
Affinity DataIC50: 1.00E+4nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent