BDBM716457 US20250034112, Compound 33b

SMILES c1cc(cc(c1)Oc2nc(nc(n2)Nc3ccc(cc3)C#N)N)C(=O)O

InChI Key InChIKey=WKFGNLUJVJDVRJ-UHFFFAOYSA-N

Data  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716457   

TargetTyrosine-protein kinase JAK2 [536-812](Human)
Yale University

US Patent
LigandChemical structure of BindingDB Monomer ID 716457BDBM716457(US20250034112, Compound 33b)
Affinity DataKd:  3.96E+4nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)