BDBM72853 2-(4-methoxyphenyl)-5-(1-piperidinyl)-4-oxazolecarbonitrile::2-(4-methoxyphenyl)-5-piperidin-1-yl-1,3-oxazole-4-carbonitrile::2-(4-methoxyphenyl)-5-piperidino-oxazole-4-carbonitrile::MLS001164859::SMR000540179::cid_726740

SMILES CCCc1cc2c(NCc3cccs3)nc(N3CCN(C)CC3)nc2cn1

InChI Key InChIKey=QDBMNUOIAPBCRM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72853   

TargetHistamine H1 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72853BDBM72853(US12492199, Example 49)
Affinity DataIC50: 1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent

TargetHistamine H4 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72853BDBM72853(US12492199, Example 49)
Affinity DataIC50: 1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent