BDBM7689 4-[N真真-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazino]benzenesulfonamide::4-[N蔵-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazino]benzenesulfonamide ::4-{2-[(3Z)-4-iodo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 25

SMILES NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3cccc(I)c23)cc1

InChI Key InChIKey=YYLOHWVUZJXESM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7689   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7689(4-[N真真-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50:  4.60nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7689(4-[N真真-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed