BDBM772837 US12421225, Example 74 (isomer A)

SMILES COc1cc([C@H]2CCn3nc(C(=O)N[C@H]4COc5ccc(C#N)cc5C4)cc3O2)ccn1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772837   

TargetSodium channel protein type 9 subunit alpha(Human)
Kaken Pharmaceutical Co.

US Patent
LigandPNGBDBM772837(US12421225, Example 74 (isomer A))
Affinity DataIC50: 1.00E+3nMAssay Description:The amount of current through human Nav1.7 was recorded using a fully automatic patch clamp device QPatch16X (Sophion Biosciences) at room temperatur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/7/2026
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Kaken Pharmaceutical Co.

US Patent
LigandPNGBDBM772837(US12421225, Example 74 (isomer A))
Affinity DataIC50: 3.00E+3nMAssay Description:The amount of current through human Nav1.5 was recorded using a fully automatic patch clamp device QPatch16X at room temperature. As the extracellula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/7/2026
Entry Details
US Patent