BDBM776928 US20250313535, Compound 638

SMILES COc1ccc(CN2CC(OC)C2)c(OC)c1-c1cccc2c(C[C@H](NC(=O)c3c(C)cccc3F)C(=O)O)cccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776928   

TargetIntegrin alpha-4/beta-7(Human)
Dice Molecules Sv

US Patent
LigandPNGBDBM776928(US20250313535, Compound 638)
Affinity DataIC50: 10nMAssay Description:MAdCAM (R&D Systems, 0.1 ug) was diluted in 50 μL PBS, added to each well of an opaque ELISA plate (Thermo), and incubated overnight at 4° C. Coated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent

TargetIntegrin alpha-4/beta-1(Human)
Dice Molecules Sv

US Patent
LigandPNGBDBM776928(US20250313535, Compound 638)
Affinity DataIC50: 100nMAssay Description:MAdCAM (R&D Systems, 0.1 ug) was diluted in 50 μL PBS, added to each well of an opaque ELISA plate (Thermo), and incubated overnight at 4° C. Coated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent