BDBM799247 N-(2-((5-cyano- 4-((2- isopropoxyphenyl) amino)pyrimidin- 2-yl)amino)- 5-(4-cyano- [1,4- bipiperidin]-1'- yl)phenyl) acrylamide::US12582654, Example 66

SMILES N#CC1CCN(C2CCN(c3ccc(Nc4ncc(C#N)c(Nc5ccccc5OC(C)C)n4)c(NC(=O)C=C)c3)CC2)CC1

InChI Key InChIKey=PIFZOBMYXSDSFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 799247   

TargetFibroblast growth factor receptor 4(Human)
Beijing Scitech-MQ Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799247BDBM799247(N-(2-((5-cyano- 4-((2- isopropoxyphenyl) amino)pyr...)
Affinity DataIC50: 10nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 4 [V550L](Human)
Beijing Scitech-MQ Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 799247BDBM799247(N-(2-((5-cyano- 4-((2- isopropoxyphenyl) amino)pyr...)
Affinity DataIC50: 30nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent