BDBM50639171 Pamiparib::Bgb-290::BGB-290

SMILES C[C@]12CCCN1CC1=NNC(=O)c3cc(F)cc4[nH]c2c1c34

InChI Key

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50639171   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Qingdao University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Qingdao University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of human PARP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-glucagon-cex from human glucagon receptor by cell based assay in presence of 0.2% bovine serum albuminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Qingdao University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639171BDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 6nMAssay Description:Inhibition of JAK1 (unknown origin) assessed as inhibition of STAT3 phosphorylation by cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)