BDBM50640214 Vociprotafib::Ptpn11 inhibitor rmc-4630::Rmc 4630::RMC-0694630::RMC-4630::RMC4630::SAR-442720::SAR442720::SAR442729

SMILES Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(CO)nc1Sc1ccnc(N)c1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50640214   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640214(Vociprotafib | Ptpn11 inhibitor rmc-4630 | Rmc 463...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of wild type SHP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50640214(Vociprotafib | Ptpn11 inhibitor rmc-4630 | Rmc 463...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed