BDBM50009126 5-Fluoro-1H-indole-2-carboxylic acid::5-fluoroindole-2-carboxylic acid::CHEMBL23507::cid_1820

SMILES OC(=O)c1cc2cc(F)ccc2[nH]1

InChI Key InChIKey=WTXBRZCVLDTWLP-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009126   

TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50009126(5-Fluoro-1H-indole-2-carboxylic acid | 5-fluoroind...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50009126(5-Fluoro-1H-indole-2-carboxylic acid | 5-fluoroind...)
Affinity DataIC50:  2.97E+5nMAssay Description:Competitive inhibition of PDK1 using [gamma-33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50009126(5-Fluoro-1H-indole-2-carboxylic acid | 5-fluoroind...)
Affinity DataKd:  2.90E+3nMAssay Description:Dissociation constant for HCV NS3 protease substrate binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed