BDBM100423 US10383835, Compound 1153::US11123311, Compound APAU::US8501783, 1153

SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=HUDQLWBKJOMXSZ-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 100423   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataKi:  19.5nMAssay Description:Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Sus scrofa (Pig))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  13nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Felis catus (Cat) (Felis silvestris catus))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  450nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Canis lupus familiaris (Dog) (Canis familiaris))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  500nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase(Equus caballus (Horse))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  121nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpoxide hydrolase(Ovis aries (Sheep))
The Regents Of The University Of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  67nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent