BDBM10452 Bivalent 4-Aminoquinoline 9f::N,N-di-4-Quinolyl-1,7-diaminoheptane dihydrochloride::N-[7-(quinolin-4-ylamino)heptyl]quinolin-4-amine dihydrochloride
SMILES C(CCCNc1ccnc2ccccc12)CCCNc1ccnc2ccccc12
InChI Key InChIKey=OQGAVEZMVJJWSH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 10452
Affinity DataKi: 126nMAssay Description:Binding affinity to human alpha1A adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Displacement of [3H]-prazosin from human alpha1A adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Binding affinity to human alpha1B adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
Affinity DataKi: 148nMAssay Description:Displacement of [3H]-prazosin from human alpha1B adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Displacement of [3H]-prazosin from human alpha1D adrenergic receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Binding affinity to human alpha1D adrenergic receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
Affinity DataKi: 832nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in COS1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 832nMAssay Description:Binding affinity to human 5HT1A receptor transfected in COS1 cells assessed as compound required to occupy 50% of receptorMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University of Science and Technology
Hong Kong University of Science and Technology
Affinity DataIC50: 1.80E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 87.8nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair