BDBM106701 CHEMBL1957352::US8586620, 51

SMILES CN1CCC(=CC1)c1c[nH]c2ccc(CN=C(N)c3cccs3)cc12

InChI Key InChIKey=KKBONEJWYQUWTK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 106701   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  1.19E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  4.97E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  8.50E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  6.47E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine 1D receptor(Bos taurus (Bovine))
Neuraxon

US Patent
LigandPNGBDBM106701(CHEMBL1957352 | US8586620, 51)
Affinity DataIC50:  220nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails US Patent