BDBM116210 US8637502, 44

SMILES O=c1n(CC#N)c2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O

InChI Key InChIKey=NDTRDFOMRIWMBU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116210   

TargetNociceptin receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116210(US8637502, 44)
Affinity DataKi:  52nM ΔG°:  -9.23kcal/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116210(US8637502, 44)
Affinity DataKi:  4.23E+3nM ΔG°:  -6.81kcal/molepH: 7.4 T: 2°CAssay Description:κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116210(US8637502, 44)
Affinity DataKi:  9.54E+3nM ΔG°:  -6.84kcal/molepH: 7.4 T: 2°CAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116210(US8637502, 44)
Affinity DataKi:  6.57E+4nM ΔG°:  -5.70kcal/molepH: 7.4 T: 2°CAssay Description:δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...More data for this Ligand-Target Pair
In DepthDetails US Patent