BDBM116395 US8637532, 76

SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccccc4)c3)ncnc12

InChI Key InChIKey=NNRYYBZUSSCWHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116395   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116395(US8637532, 76)
Affinity DataIC50:  1.90E+3nMpH: 7.5 T: 2°CAssay Description:The kinase assay is performed as 384-well Flashplate assay (PerkinElmer LAS Germany GmbH). 3.4 nM His6-PDK1(Delta 1-50) (PDK1 that has a His-tag cons...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM116395(US8637532, 76)
Affinity DataIC50:  54.6nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In DepthDetails US Patent