BDBM12586 (2R,3S)-3-amino-2-hydroxy-N-(4-methoxy-2,3,6-trimethylphenyl)-4-phenylbutane-1-sulfonamido::CHEMBL379692::N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE::methoxy-trimethyl benzenesulfonamide analogue 4

SMILES COc1cc(C)c(c(C)c1C)S(=O)(=O)NC[C@@H](O)[C@@H](N)Cc1ccccc1

InChI Key InChIKey=HORGTFOBJRCVMO-ZWKOTPCHSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12586   

TargetProthrombin(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM12586((2R,3S)-3-amino-2-hydroxy-N-(4-methoxy-2,3,6-trime...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM12586((2R,3S)-3-amino-2-hydroxy-N-(4-methoxy-2,3,6-trime...)
Affinity DataIC50:  1.20E+4nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair