BDBM126081 US8779142, 100

SMILES CC(C)c1nn(-c2ccc(cc2C)C(N)=O)c2nccc(-n3cnc(c3)-c3cnn(C)c3)c12

InChI Key InChIKey=JZYLVXOKNXFKFF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126081   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM126081(US8779142, 100)
Affinity DataIC50:  98nMAssay Description:Displacement of biotin-labeled geldanamycin from His-tagged HSP90alpha NTD (unknown origin) preincubated for 2 hrs followed by biotin-labeled geldana...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM126081(US8779142, 100)
Affinity DataIC50:  150nMpH: 7.5Assay Description:The HSP90-binding activity was measured by an AlphaScreen competitive assay system. The purified HSP90 solution was diluted with a binding buffer (50...More data for this Ligand-Target Pair